5 Reasons that Cialis Did Not Help You with Erections Or Stopped Working
Stop tadalafil and call your doctor immediately for any hearing loss, decrease in hearing, or ringing in the ears.
What do Penile Problems Look Like?
Tadalafil tends to work better for men who want flexibility without planning around a 4 to 6 hour window, are sexually active multiple times per week, are also managing BPH symptoms, or simply want the experience to feel more spontaneous. ED medications are prescription drugs for a reason. While both sildenafil and tadalafil are generally well-tolerated, your health history, current medications, and the underlying cause of your ED all matter. For some men, erectile dysfunction is an early signal of cardiovascular disease, diabetes, or a hormonal imbalance. A urologist can look at the full picture, not just the symptom.
What if I miss a dose?
At Advanced Urology, our specialists work with patients to understand what's driving their ED and what treatment approach makes the most sense for their situation. If you're ready to get answers, we're ready to help. Schedule a consultation with Advanced Urology today. Generic name: tadalafil [ ta-DAL-a-fil ] Brand names: Adcirca, Cialis Drug classes: Agents for pulmonary hypertension, Impotence medications Tadalafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Tadalafil under the name of Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Do not start or stop taking tadalafil during pregnancy without your doctor's advice.
| Country | Legal Status | Purchase Restrictions | Notes |
|---|---|---|---|
| USA | Prescription medication | Requires prescription | Available in pharmacies |
| UK | Prescription medication | Over-the-counter sales illegal without prescription | Only available via prescription |
| Canada | Prescription-only | Controlled substance | Prescription required |
| Australia | Prescription-only | Restricted sale | Controlled under drug laws |
Having pulmonary arterial hypertension (PAH) during pregnancy may cause heart failure, stroke, or other medical problems in both mother and baby. Tell your doctor right away if you become pregnant.
| Reaction | Number of Cases | Severity | Comments |
|---|---|---|---|
| Priapism (prolonged erection) | Rare | Severe | Needs emergency treatment |
| Vision disturbances | Few reports | Variable | Blue tint or blurred vision |
| Hearing loss | Rare | Severe | Sudden deafness reported in some cases |
| Cardiac events | Very rare | Severe | Chest pain, arrhythmia, requires immediate medical attention |
It may not be safe to breastfeed while using tadalafil. Tadalafil is not approved for use by anyone younger than 18 years old. Tadalafil is usually taken only once per day.
| Parameter | Value | Notes |
|---|---|---|
| Absorption Time | About 30-120 minutes | Peak plasma levels reached within this period |
| Half-life | Approximately 17.5 hours | Long duration, effects up to 36 hours |
| Bioavailability | Around 81% | Percentage of unchanged drug absorbed |
| Metabolism | Liver (Cytochrome P450 system) | Mainly via CYP3A4 enzyme |
| Excretion | Feces (61%), Urine (36%) | Mostly in inactive metabolites |
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Tadalafil can be taken with or without food.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 10mg | 120 + 6 Pills | 178.49€ 169.99€ | |
| Tadalista Super Active | 20mg | 90 + 10 Pills | 314.14€ 299.18€ | |
| Cialis Generic | 20mg | 60 + 6 Pills | 117.76€ 112.15€ | |
| Cialis Generic | 2.5mg | 120 + 6 Pills | 128.93€ 122.79€ | |
| Tadalista Super Active | 20mg | 180 + 20 Pills | 521.59€ 496.75€ | |
| Cialis Generic | 40mg | 60 + 6 Pills | 130.98€ 124.74€ | |
| Cialis Generic | 60mg | 90 + 6 Pills | 196.67€ 187.30€ | |
| Tadalista Super Active | 20mg | 10 Pills | 55.64€ 52.99€ | |
| Tadalista Super Active | 20mg | 30 + 6 Pills | 128.09€ 121.99€ | |
| Cialis Generic | 5mg | 270 + 10 Pills | 205.81€ 196.01€ | |
| Cialis Generic | 60mg | 180 + 10 Pills | 313.11€ 298.20€ | |
| Cialis Generic | 5mg | 20 Pills | 41.99€ 39.99€ | |
| Cialis Generic | 40mg | 120 + 8 Pills | 206.98€ 197.12€ | |
| Cialis Generic | 10mg | 180 + 8 Pills | 236.88€ 225.60€ | |
| Cialis Generic | 60mg | 120 + 8 Pills | 240.18€ 228.74€ |
For erectile dysfunction, take Cialis just before sexual activity but not more than once per day.
Are All Tadalafil Prescriptions the Same?
Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take tadalafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Some medicines can cause unwanted or dangerous effects when tadalafil 10mg daily used with tadalafil. Tell your doctor about all your current medicines, especially riociguat (Adempas).
What could be improved
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis. Get medical help at once if you have nausea, chest pain, or dizziness during sex. Stop using tadalafil and get emergency medical help if you have sudden vision loss. You should not take tadalafil if you are allergic to it. It can be used up to 36 hours before sexual activity. Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.
More about Cialis (tadalafil)
On the more serious end, both medications can cause a dangerous drop in blood pressure when combined with nitrate medications, which are often prescribed for chest pain or certain heart conditions. If you take alpha-blockers for blood pressure or prostate issues, talk to your urologist about safe dosing before starting either medication. Brand-name Viagra and Cialis can be expensive out of pocket. Both are now widely available as generics, which has brought costs down substantially. Generic sildenafil and generic tadalafil are chemically identical to their brand-name versions, same active ingredient, same doses, same FDA manufacturing standards.
How much do Tadalafil and Sildenafil cost?
The savings can be significant, often reducing the per-pill cost to a fraction of the original price. Clinical studies have shown comparable efficacy between sildenafil and tadalafil. A head-to-head trial published by the NIH found that both medications produced similar improvements in erectile function scores, though patient preference often tilted toward tadalafil because of its longer duration. The right choice depends on how you want the medication to fit into your life. Sildenafil tends to be a better fit for men who prefer taking a medication only when they anticipate sexual activity, want a shorter window in their system, or are looking for the lowest possible cost at the pharmacy. Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.
Mechanism of action
If you're managing both ED and BPH symptoms like urinary urgency or frequent nighttime urination, a single daily dose of tadalafil may address both conditions at once. Both medications share a similar side effect profile because they work through the same mechanism. The most common side effects include headache, facial flushing, nasal congestion, and upset stomach. These tend to be mild and short-lived for most patients. Sildenafil has one fairly well-known additional side effect: a temporary blue-green color tint or light sensitivity.
US Brand Name
This is caused by mild PDE6 inhibition in the retina. It's dose-dependent and not dangerous, but noticeable for some users. Daily low-dose tadalafil avoids the "spikes" of on-demand pills, reducing the risk of sudden side effects like headaches or flushing. By maintaining a steady level, your body adapts more easily, though muscle or back aches are more common with tadalafil than other options. This consistent approach offers a smoother experience with fewer peaks in medication levels. Store at room temperature away from moisture and heat. If tadalafil is used as needed, you are not likely to be on a dosing schedule. If you take tadalafil every day and you miss a dose, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.
Vision Problems
Taking tadalafil with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take this medicine if you also use: riociguat (to treat pulmonary arterial hypertension); or riociguat (to treat pulmonary arterial hypertension); or a nitrate drug (for chest pain or heart problems) such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs such as amyl nitrate or nitrite "poppers". a nitrate drug (for chest pain or heart problems) such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs such as amyl nitrate or nitrite "poppers". Some tadalafil can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). To make sure this medicine is safe for you, tell your doctor if you have ever had: angina (chest pain), high or low blood pressure; angina (chest pain), high or low blood pressure; pulmonary hypertension (unless you are taking tadalafil for this); pulmonary hypertension (unless you are taking tadalafil for this); a condition called pulmonary veno-occlusive disease (narrowing of the veins that carry blood from the lungs to the heart); a condition called pulmonary veno-occlusive disease (narrowing of the veins that carry blood from the lungs to the heart); liver or kidney disease (or if you are on dialysis); liver or kidney disease (or if you are on dialysis); vision loss, or retinitis pigmentosa (an inherited condition of the eye); vision loss, or retinitis pigmentosa (an inherited condition of the eye); a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a physical deformity of the penis (such as Peyronie's disease), or an erection lasting longer than 4 hours; a physical deformity of the penis (such as Peyronie's disease), or an erection lasting longer than 4 hours; health problems that make sexual activity unsafe.
How does Cialis work?
health problems that make sexual activity unsafe. Sudden vision loss has occurred tadalafil daily in a small number of people taking medicines like tadalafil (Viagra or others). Most of these people already had certain eye problems or risk factors for blood vessel disorders (heart disease, diabetes, high blood pressure, high cholesterol, coronary artery disease, smoking, or being over 50 years old). It is not clear whether the medicine was the actual cause of vision loss. Sudden hearing loss has also been reported with tadalafil. Do not take extra medicine to make up the missed dose.
- Tadalafil may interact with other medications like alpha-blockers.
- It is important to avoid grapefruit or grapefruit juice while taking tadalafil.
- Side effects are usually mild but seek medical help for serious reactions.
- Allergic reactions to tadalafil are rare but possible.
- Tadalafil does not cause spontaneous erections without sexual arousal.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Drinking alcohol with this medicine can cause a drop in blood pressure, leading to dizziness or fainting. Grapefruit and grapefruit juice may interact with tadalafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine. Get emergency medical help if you have signs of an allergic reaction to tadalafil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
- If a dose is missed on the daily regimen, it can be taken as soon as remembered unless it's almost time for the next.
- The goal of treatment is to restore a satisfactory sexual life for the patient and their partner.
- Research into new formulations and uses for tadalafil and similar compounds is ongoing.
Stop and get medical help at once if you have nausea, chest pain, or dizziness during sex. You could be having a life-threatening side effect. Stop using tadalafil and call your doctor at once if you have: a light-headed feeling, like you might pass out; a light-headed feeling, like you might pass out; an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); ringing in your ears or sudden hearing loss; or ringing in your ears or sudden hearing loss; or heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
- The decision between daily and on-demand dosing is based on frequency of sexual activity and personal preference.
- Generic tadalafil must meet the same FDA standards for safety, strength, and quality as the brand-name drug.
- Keep a list of your medications with you to show any healthcare provider you visit.
heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
