Understanding Levitra Brand Medication for ED
DHEA, herbal will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. diltiazemdiltiazem will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors diltiazem will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dofetilidedofetilide increases toxicity of vardenafil by QTc interval. dofetilide increases toxicity of vardenafil by QTc interval. donepezildonepezil and vardenafil both increase QTc interval. dordavipronedordaviprone and vardenafil both increase QTc interval. Increase the frequency of ECG and electrolyte monitoring. dordaviprone and vardenafil both increase QTc interval. doxepindoxepin and vardenafil both increase QTc interval.
Can I get a prescription in the USA and use it to buy medication from Canada?
doxepin and vardenafil both increase QTc interval. dronedaronedronedarone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Original | 20mg | 92 + 4 Pills | 406.22€ 386.88€ | |
| Levitra Original | 20mg | 4 Pills | 45.87€ 43.69€ | |
| Levitra Generic | 40mg | 20 Pills | 67.56€ 64.34€ | |
| Levitra Professional | 20mg | 180 + 4 Pills | 502.31€ 478.39€ | |
| Levitra Generic | 60mg | 180 + 10 Pills | 501.43€ 477.55€ | |
| Levitra Generic | 10mg | 10 Pills | 28.93€ 27.55€ | |
| Levitra Generic | 60mg | 10 Pills | 47.42€ 45.16€ | |
| Levitra Professional | 20mg | 120 + 4 Pills | 348.44€ 331.85€ | |
| Levitra Generic | 20mg | 270 + 10 Pills | 376.33€ 358.41€ | |
| Levitra Generic | 60mg | 60 + 4 Pills | 198.85€ 189.38€ | |
| Levitra Generic | 10mg | 120 + 10 Pills | 178.59€ 170.09€ |
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dronedarone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
What are the main differences between Levitra and Cialis?
fostamatinibfostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostemsavirvardenafil and fostemsavir both increase QTc interval. Vardenafil dose may need to be reduced if coadministered with levitra order uk moderate or strong CYP3A4 inhibitors duvelisibduvelisib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration with duvelisib increases AUC of a sensitive CYP3A4 substrate which may increase the risk of toxicities of these drugs. Consider reducing the dose of the sensitive CYP3A4 substrate and monitor for signs of toxicities of the coadministered sensitive CYP3A substrate. duvelisib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. efavirenzefavirenz will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.efavirenz and vardenafil both increase QTc interval. efavirenz will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Further information
Limit vardenafil dose to 5 mg/24 hr erythromycin lactobionateerythromycin lactobionate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin stearateerythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr escitalopramescitalopram increases toxicity of vardenafil by QTc interval. escitalopram increases toxicity of vardenafil by QTc interval.
Are there reasons why Cialis is a better treatment option than Levitra or vice versa?
eslicarbazepine acetate will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Transient decrease in heart rate and AV conduction delays may occur when initiating etrasimod. Owing to potential of additive effect on heart rate, etrasimod may increase risk of QT prolongation and Torsades de Pointes when coadministered with Class Ia or Class III antiarrhythmic drugs, or other drugs that prolong the QT interval. etravirineetravirine will decrease the level levitra 60 mg online or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. etravirine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
What should I know about vardenafil before taking it?
fedratinibfedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazolefexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fingolimodfingolimod and vardenafil both increase QTc interval. elagolixelagolix decreases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
| Aspect | Details | Notes |
|---|---|---|
| Product Name | Levitra 20 | Branded variant of vardenafil |
| Manufacturer | Bayer Pharmaceuticals | Global pharmaceutical company |
| Active Ingredient | Vardenafil | Main component for ED treatment |
| Release Year | 2003 | When first launched |
| Typical Dosage | 20 mg | Standard dose for ED |
Consider increasing CYP3A substrate dose if needed. elagolix decreases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Adjust vardenafil dose for ED; not to exceed single dose of 2.5 mg in 72 hr Encorafenib both inhibits and induces CYP3A4 at clinically relevant plasma concentrations. Coadministration of encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents. Encorafenib both inhibits and induces CYP3A4 at clinically relevant plasma concentrations. entacaponeentacapone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
- The effectiveness of Levitra 20 mg varies based on individual health factors.
- Levitra 20 mg is sometimes used off-label for pulmonary hypertension treatment.
- It is important to follow the prescription instructions carefully to minimize side effects.
- Levitra 20 mg is not a cure for erectile dysfunction but helps manage symptoms temporarily.
- Consumers should be aware of counterfeit versions of Levitra 20 mg on the market.
- Regular check-ups with a healthcare provider are recommended while using Levitra 20 mg.
- It is advisable to avoid driving or operating machinery after taking Levitra 20 mg.
- The pill should be taken whole with water; do not crush or split the tablet.
- Patients with liver or kidney issues should consult their doctor before use.
- Levitra 20 mg has a rapid onset, making it a convenient option for many men.
- Using Levitra 20 mg responsibly can enhance sexual confidence and satisfaction.
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors entacapone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors erythromycin baseerythromycin base will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
How should I use Levitra?
Consider reducing the dose of the sensitive CYP3A4 substrate and monitor for signs of toxicities of the coadministered sensitive CYP3A substrate. duvelisib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. efavirenzefavirenz will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.efavirenz and vardenafil both increase QTc interval. efavirenz will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
What is Levitra
elagolixelagolix decreases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Consider increasing CYP3A substrate dose if needed. elagolix decreases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Adjust vardenafil dose for ED; not to exceed single dose of 2.5 mg in 72 hr Encorafenib both inhibits and induces CYP3A4 at clinically relevant plasma concentrations. Coadministration of encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents.
Does Levitra have fewer side effects than Viagra?
Encorafenib both inhibits and induces CYP3A4 at clinically relevant plasma concentrations. entacaponeentacapone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors entacapone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors erythromycin baseerythromycin base will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin base will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin base will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin lactobionateerythromycin lactobionate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Medical uses
DHEA, herbal will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. diltiazemdiltiazem will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors diltiazem will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dofetilidedofetilide increases toxicity of vardenafil by QTc interval. dofetilide increases toxicity of vardenafil by QTc interval.
What should I do if I miss a dose of vardenafil?
donepezildonepezil and vardenafil both increase QTc interval. dordavipronedordaviprone and vardenafil both increase QTc interval. Increase the frequency of ECG and electrolyte monitoring. dordaviprone and vardenafil both increase QTc interval. doxepindoxepin and vardenafil both increase QTc interval.
How is vardenafil supplied (dosage forms)?
doxepin and vardenafil both increase QTc interval. dronedaronedronedarone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dronedarone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with levitra order uk moderate or strong CYP3A4 inhibitors duvelisibduvelisib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration with duvelisib increases AUC of a sensitive CYP3A4 substrate which may increase the risk of toxicities of these drugs. Limit vardenafil dose to 5 mg/24 hr erythromycin stearateerythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr erythromycin stearate will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 5 mg/24 hr escitalopramescitalopram increases toxicity of vardenafil by QTc interval. escitalopram increases toxicity of vardenafil by QTc interval. eslicarbazepine acetate will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Transient decrease in heart rate and AV conduction delays may occur when initiating etrasimod.
- Levitra 20 mg may be used for off-label purposes under medical supervision.
- The medication’s cost varies depending on the pharmacy and location.
- Levitra 20 mg is not suitable for individuals with known hypersensitivity to vardenafil.
- Women and men without erectile dysfunction should not use Levitra 20 mg.
- It is important to monitor blood pressure when using Levitra 20 mg, especially with other medications.
- Levitra 20 mg may cause nasal congestion and mild vision changes as common side effects.
- The medication should be stored out of reach of children to prevent accidental ingestion.
- Always complete your full course of treatment as prescribed by your doctor.
- Levitra 20 mg can be part of a broader sexual health treatment plan.
- Avoid alcohol for best results and reduced risk of side effects.
- Consult your healthcare provider if you experience persistent or severe adverse effects.
Owing to potential of additive effect on heart rate, etrasimod may increase risk of QT prolongation and Torsades de Pointes when coadministered with Class Ia or Class III antiarrhythmic drugs, or other drugs that prolong the QT interval. etravirineetravirine will decrease the level levitra 60 mg online or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
- Levitra 20 mg's patent and branding may vary across countries and markets.
- It’s recommended to watch for any allergic reactions such as rash or swelling.
- Patients should inform their doctor of any history of stroke or heart attack before use.
- Levitra 20 mg is a prescription medication; do not buy it without medical advice.
- The medication’s effectiveness can be enhanced with regular exercise and healthy lifestyle.
- Levitra 20 mg is sometimes compared with other ED drugs like Viagra and Cialis.
- The pill should be taken on an empty stomach or after a light meal for best results.
- Users are advised to consult their doctor if they experience no effect after 30-60 minutes.
- Levitra 20 mg is often preferred over other brands for its rapid onset.
- It’s essential to follow all dosing guidelines to prevent overdose.
- Men should consult healthcare providers for personalized advice on Levitra 20 mg.
etravirine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fedratinibfedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fedratinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazolefexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fexinidazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fingolimodfingolimod and vardenafil both increase QTc interval. fingolimod and vardenafil both increase QTc interval. fluconazolefluconazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
| Use Case | Description | Target Population | Recommended Dosage |
|---|---|---|---|
| Erectile Dysfunction (ED) | To improve blood flow for erection | Men aged 40-70 | 20 mg as needed |
| Pulmonary Hypertension (Rare) | Off-label for pulmonary hypertension | Patients under doctor care | As prescribed |
| Male Libido Enhancement | Sometimes used off-label for libido boost | Adults seeking enhancement | Under medical supervision |
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluconazole will increase the bayer levitra 20mg level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fludrocortisonefludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fluvoxaminefluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavirfosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
- Levitra 20 mg can cause unexpected side effects like chest pain; seek immediate help if this occurs.
- The medication interacts with certain blood pressure medicines, requiring medical supervision.
- It is important to avoid sharing Levitra 20 mg with others to prevent adverse effects.
- Patients should disclose all health conditions and medications during consultation.
- Its use is not recommended for women or children under any circumstances.
- Levitra 20 mg does not protect against sexually transmitted infections.
- Using Levitra 20 mg with recreational drugs can be dangerous and is strongly discouraged.
- Reports indicate that some users experience priapism, a prolonged erection requiring emergency treatment.
- The recommended starting dose for most men is usually 10 mg, increasing to 20 mg if needed.
- Combining Levitra 20 mg with other ED medications is not advised.
- Always follow the guidance of a healthcare professional when using Levitra 20 mg.
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitantfosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosfomycinfosfomycin and vardenafil both increase QTc interval.
How Vardenafil and Viagra Work
fingolimod and vardenafil both increase QTc interval. fluconazolefluconazole will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluconazole will increase the bayer levitra 20mg level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fludrocortisonefludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fludrocortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Less common
fluvoxaminefluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fluvoxamine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavirfosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosamprenavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitantfosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Drug Interactions
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosaprepitant will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fosfomycinfosfomycin and vardenafil both increase QTc interval. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosfomycin and vardenafil both increase QTc interval. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosphenytoinfosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosfomycin and vardenafil both increase QTc interval. The risk of QT prolongation may increase in patients with electrolyte abnormalities (such as hypokalemia and hypocalcemia), patients with conditions that have potential to cause electrolyte imbalance (such as renal impairment), or patients taking other drugs affecting electrolyte balance or QT prolongation; avoid this drug in patients with known QT prolongation or ventricular arrhythmias, including a history of torsade de pointes; monitor electrolytes during treatment fosphenytoinfosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fosphenytoin will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fostamatinibfostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostamatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors fostemsavirvardenafil and fostemsavir both increase QTc interval.
